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KMID : 1156220040300050374
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Journal of Environmental Health Sciences
2004 Volume.30 No. 5 p.374 ~ p.377
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A Study on the Durability and Synthesis of Sulfa Agents Using Glutaraldehyde
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Yoon Cheol-Hun
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Abstract
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Dual actions are the most recently used delivery system in drug study. Dual-action agents are unique chemical entities comprised of two different type of antibacterial compounds covalently linked together in a single molecule in such a way that both components are able to exert their bactericidal properties. Crosslinked sulfadiazine-sulfanilamide such as antibiotics is synthesized by synthetic handle with glutaraldehyde. As a result, New synthetic antibacterial agent exhibited the broad antibacterial activities against Gram(+) and Gram(?) of 4 strains and a long durability supposing that the stomach and blood.
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